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It is not a true vitamin but rather a vitamin-like substance

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Accordingly, the degree of DPP-4 inhibition attained in vivo is sufficient to increase circulating levels of intact (active) incretins by 2- to 4-fold and result in improved glycaemic control (118)

It has been known that among the neural centers, LCs concentration is highest is in the hypothalamus [77]

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Moreover, MC3R might influence feeding behavior, possibly impacting appetite and food intake, and is thought to be involved in various metabolic processes, including the potential regulation of glucose and lipid metabolism