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Eye Res
Glucagon-like peptide-1 receptor agonists decrease hyperinsulinemia and hyperandrogenemia in dehydroepiandrosterone-induced polycystic ovary syndrome mice and are associated with mitigating inflammation and inducing browning of white adipose tissuedagger
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Multiple approaches were investigated across academic and industrial laboratories, including enteric coatings to bypass stomach acid, protease inhibitor co-formulations, nanoparticle encapsulation, mucoadhesive delivery systems, and permeation enhancers
No additional updates are warranted to product information for any GLP-1 drug, the agency saidboth Wegovy and Ozempic already indicate on their safety labels the drugs have caused thyroid tumors in studies with rodents, but note it is unknown whether the drugs can cause thyroid tumors or thyroid cancer
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