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The assessment results are available in the Supplementary Appendix S2, S3
After matching, average age at index prescription for non-diabetic, obese men was 37.8 7.8 and average BMI at index prescription was 38.6 5.6
There is also a trial specifically testing whether retatrutide prevents heart attacks and strokes (TRIUMPH-3, 1,800 people), and a head-to-head trial comparing retatrutide directly against tirzepatide (the active ingredient in Zepbound) under identical conditions (NCT06662383, 800 patients)
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A recent study has discovered that adenosine can activate brown fat cells in mice through the A2a receptor, thereby preventing obesity due to a high-fat diet [11]
USA 112 , E2245E2252 (2015)
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