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84.6% of patients achieved more than 5% weight loss compared to 25% on lifestyle changes alone
Nature 406 , 906910 (2000)
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Moreover, Ex-4 induces autophagy and attenuates ovarian cancer cell viability by upregulating the expression of autophagic markers beclin-1 and microtubule-associated proteins light chain 3I/II (LC3I/II), while simultaneously downregulating the expression of p62 (a linker protein for LC3II) [68]
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