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The final sample size was based on the assumption that 14% of the patients in the placebo group and 38% of the patients in the semaglutide 0.4-mg group would meet the criteria for the primary end point, after we accounted for a dropout rate of up to 15%

Oral contraceptives, which interfere with B6 metabolism, have also been associated with low levels

Studies show patients who push through initial nausea achieve comparable weight loss outcomes to those with minimal side effects

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