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Cytotoxicity was assessed by measuring lactate dehydrogenase release as previously described [15] and CSE treated cells under conditions tested did not have changes in cell viability that were statistically significantly different from controls and was greater than 85%

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In addition to these cellular functions, GSTO1 has been shown to play a significant role in the regulation of IL-1 processing and secretion 12,13

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Most of the ingested tripeptide is hydrolyzed in the gut lumen by gamma-glutamyltransferase before absorption [5]