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Loren Pickart first isolated and identified GHK-Cu in 1973, discovering that this peptide complex demonstrated wound healing properties far exceeding what either component achieved alone

BMC Oral Health 20(1):65

Ann Rheum Dis (2010) 69(11):20136

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As it was previously reported, NADP + must dissociate from the active site prior to deprotonation of the C159 residue that forms the thiolate-FAD charge transfer complex, implicating roles for Y296 in the efficiency of reduction and in the dissociation of NADP +

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