Philadelphia, PA: Wolters Kluwer/Lippincott Williams & Wilkins
Young blood rescues the cognition of Alzheimers model mice by restoring the hippocampal cholinergic circuit
Enhanced skeletal muscle insulin sensitivity after acute resistance-type exercise is upregulated by rapamycin-sensitive mTOR complex 1 inhibition
Ozempic is primarily a medication for type 2 diabetes, and any off-label use for weight loss in non-diabetic individuals should be under strict medical supervision, with dosages being similar to those advised for diabetic patients looking to manage their weight
Patent terms, supplementary protection certificates (the European equivalent of patent term extensions), regulatory exclusivity periods, and the timing of initial product approvals all vary by country
Zepbound severe diarrhea including watery diarrhea, liquid diarrhea, or explosive episodes increases the risk of dehydration and, rarely, acute kidney injury, a complication explicitly noted in the FDA Zepbound prescribing information