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These drugs can help make you feel fuller for longer, slow the movement of food through the digestive system, and reduce cravings

This titration minimises gastrointestinal side effects and allows the body to adapt

What failure looks like at Step 4: Pain becomes continuous rather than episodic, fever develops, labs worsen, or the patient cannot tolerate oral intake

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DB enhances insulin release through mechanisms involving KATP channels, bitter taste receptor signaling, and intraislet GLP-1 secretion

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