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While mutations of ETC proteins are rarely linked as a direct cause of PD (except for UQCRC1), impaired ETC proteins may not only lead to excessive ROS production, but also cause impeded mitophagy, -Syn aggregation, and apoptosis in PD pathogenesis

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Biochemia Medica 25(2):141151 Guo X, Yu Y, Liu X, Zhang Y, Guan T, Xie G, Wei J (2014) Heterologous expression and characterization of human cellular glutathione peroxidase mutants

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35,100 This enzyme is particularly important because it regulates the concentration of 2,3-BPG of erythrocytes

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