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Vitamin A and Retinoic Acid Multidimensional Regulation of Protein Synthesis by Retinoic Acid Retinoic Acid (RA) regulates gene expression through nuclear receptors RAR/RXR heterodimers: Amino Acid Transporter Programming: RA directly activates the SLC7A5 (LAT1) gene, which encodes a transporter responsible for the transmembrane transport of branched-chain amino acids (leucine, isoleucine), thus affecting the activation efficiency of the mTORC1 signaling pathway