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GLP-1R agonists mimic hormones that activate biological responses in GLP-1R
Obesity is a major risk factor for type 2 diabetes, cardiovascular diseases, and other comorbidities, creating a pressing need for therapeutic solutions that manage multiple conditions simultaneously
Nies AT, Koepsell H, Damme K, Schwab M
The active ingredient in Zepbound, Tirzepatide , which is also present in the drug Mounjaro, prescribed off-label for weight loss, functions by mimicking glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)
Ethics declarations Ethics approval All experimental procedures were performed in accordance with international guidelines for the care and use of laboratory animals, including the ARRIVE guidelines, and were consistent with national regulations
November 2011
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