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The highlighted region indicates the distinctive triple-proline motif (P3-P4-P5) that confers exceptional structural rigidity and acid stability

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the second look catches stability problems that emerged during refrigeration

Micrographs were acquired on a Titan Krios microscope (FEI) operated at 300 kV with a K3 direct electron detector (Gatan), using a slit width of 20 eV on a GIF-Quantum energy filter