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217 , e20190613 (2020)

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Human, topical, cosmetic: a set of 12-week facial-cream studies in photoaged skin, the most frequently cited of which enrolled 71 women

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However, high dose vitamin E supplements those which provide more than 300 mg per day can interact with the blood thinners aspirin and warfarin ( They can also interfere with tamoxifen, a drug used to treat breast cancer, and cyclosporine, an immunosuppressant used by people who have received an organ transplant ( If you have any concerns about potential interactions between vitamin E supplements and your medications, you should consult your healthcare provider

Some protocols call for 24 hours maximum at room temperature