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2016;11(9):e0162590
The safety profile of the individual KLOW components is well-established in research settings, but the combination is less studied
10.1016/bs.acc.2018.07.004 31
Additionally, the protective effects of estrogens in PD are also related to the activation of the mitogen-activated protein kinase (MAPK) signaling pathway and the consequent upregulation of Bcl-2, as demonstrated in dopaminergic cells in mesencephalic slice cultures (Wang et al., 2011)
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