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Carrying excess body weight requires greater physical effort for daily activities, and reducing this burden often results in improved mobility and reduced fatigue

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Clinicians should be aware of important safety considerations, including the risk of gallbladder disease (cholelithiasis, cholecystitis) and rare reports of intestinal obstruction or ileus

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6 For adults with heart disease and obesity or overweight, along with a reduced-calorie diet and increased physical activity