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More significantly, RA patients already on DMARDs (disease-modifying antirheumatic drugs) who added a GLP-1 agonist had fewer disease flares than those on DMARDs alone

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Patients experiencing severe gastrointestinal adverse effects should maintain adequate hydration to prevent dehydration and potential renal impairment

To help provide insights into the potential role of oral semaglutide in current T2D management, this article aims to discuss the pharmacology of oral semaglutide, review the current clinical evidence on the efficacy and safety of this agent from the extensive phase III PIONEER clinical trial program in patients with T2D, and describe findings from initial cost-effectiveness studies

However, the most significant and lasting improvements usually become more apparent over several months of consistent use

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