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reported only minor cardiovascular effects despite increased insulin levels and reduced plasma glucose concentration, in patients without diabetes but with compensated heart failure [80]
This is significantly longer than peptides reconstituted in plain sterile water, which typically degrades faster without the bacteriostatic preservative
Standard reconstitution uses 2 mL of bacteriostatic water per 5 mg vial, producing a concentration of 2.5 mg per mL or 0.25 mg per 0.1 mL (10 units on an insulin syringe)
Pairing them is hypothesized not proven to give broader coverage than either alone
& Gorelick, F
Diabetologia 66 , 17801795 (2023)
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