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The stimulant effect provides an immediate drop in appetite, leading to a quick reduction in the number on the scale

Koeth, E.B

Over time, the body develops some tolerance to the gastric slowing effect, so their gastric emptying delay is less acute (and thus they have milder postprandial effect relative to short-acting ones) ( [112] ) ( [113] )

When used for overweight or obesity, the drugs are typically prescribed in higher doses than when prescribed for diabetes

Antioxidants (Basel) 10 (8), 1175

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