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Finally, the certainty of the outcomes was categorized into four classes based on evidence classification criteria: Class I (convincing evidence), Class II (highly suggestive evidence), Class III (suggestive evidence), Class IV (weak evidence), and NS (non-significant) 58,61

This isn't just a trend among teenagers or young adults

These often appear when doses exceed recommended limits or when supplements are taken on an empty stomach

At the same time, macro-plastics are polluting land, water, and air, fueling a surge in infectious diseases, especially in low- and middle-income countries

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