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So far, AOD-9604 has not been shown to produce the same IGF-1 response

Li QX, Gao H, Guo YX, Wang BY, Hua R, Gao L, et al

Then, query two commonly used target prediction databases, SwissTargetPrediction and Batman-TCM, to obtain 41 and 11 potential targets, respectively

3.4 Other regulatory mechanisms of ferroptosis There are several classical signaling pathways, which either synergize with ferroptosis or act as upstream regulatory signals that influence cancer cell survival and proliferation, including PI3K/Akt, Wnt/-catenin, p53, ACSL4, Caspase-1-dependent pyroptosis, and AMP-activated protein kinase (AMPK)/ Beclin1 (BECN1) signal pathways

Dalmasso G, Charrier-Hisamuddin L, Nguyen HT, et al

Brevetti, G., di Lisa, F., Perna, S., Menabo, R., Barbato, R., Martone, V