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That said: human data remains limited, sample sizes are small, and no studies have directly compared direct glutathione supplementation against precursor approaches on meaningful clinical endpoints
Mu L, Wang G, Yang X, Liang J, Tong H, Li L, et al
At this time, there is not enough clinical evidence to determine how long L-arginine may take to affect sexual function in women
While the mechanism is not yet proven, there is support for the idea that GLP-1 attenuates the ras homolog gene family, member A (RhoA)/Rho-associated protein kinase (ROCK) signaling pathway, whose activation is known to reduce levels of occludin, claudin-5, and zonula occludens-1 (ZO-1), as well as promote disruption of endothelial tight junctions
PMID: 12877710
A: The key difference is half-life and dosing frequency
