For bariatric surgery patients, GLP-1 medication prescriptions were tracked within 365 days before or after surgery, and each patient was categorized as taking a GLP-1 medication before their procedure, after their procedure, both before and after their procedure or as never having taken a GLP-1 medication
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It does not interfere with GLP-1 or GIP receptor binding, does not alter tirzepatide pharmacokinetics, and does not compete for the same metabolic enzymes
doi: 10.1186/s13098-020-00603-6 352 YanFLiNShiJLiHYueYJiaoWet al
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The primary goals were to demonstrate the superiority of tirzepatide in mean percentage body weight reduction from the baseline and in the percentage of participants achieving over 5% body weight loss at 72 weeks compared to placebo