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The GIP receptor component is believed to enhance metabolic and weight-loss effects, whilst glucagon receptor activation is hypothesised to increase energy expenditure and promote hepatic fat breakdown (lipolysis)
That balance looks different for everyone
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This creates a beneficial cycle: better gut function supports better brain function, which in turn may improve gut-brain signaling
Image source: GLP-1s and Food Noise One of the interesting impacts of the GLP1 medications is the reduction of what is called food noise, also known as food-related intrusive thoughts or food preoccupation (Mozafariun 2025)
BPC-157 shows particular promise for disc healing because it stimulates angiogenesis, the formation of new blood vessels, potentially improving nutrient delivery to avascular disc tissue
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