Fat loss is usually the more meaningful goal
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For example, individuals in the cohorts were older and mostly white men, thus hurting the results generalizability to the general population, while the researchers could not rule out residual confounding
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Gastroenterology 134 , 11591168, doi: 10.1053/j.gastro.2008.01.011 (2008)
75-LB: CT-388, A novel once-weekly dual GLP-1 and GIP receptor modulator, is safe, well-tolerated, and produces more than 8% weight loss in four weeks in overweight and obese adults