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To determine the kinetic parameters, the reaction mixture (300 L), consisting of 100 mM HEPESKOH (pH 7.5), 0.2 mM NADH, 20 U mL 1 l-lactate dehydrogenase, 0.00781.0 mM l-cystine, and appropriate concentrations of CGL (50 and 190 g mL 1 in the case of wild-type and the Y97F variant, respectively), was incubated at 37 C

doi:10.1124/pharmrev.121.000408 Longo N, Frigeni M, Pasquali M

These side effects can lead to fluid loss, making you thirsty

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Yu D, Shen S, Zhang J, Wang Q

Nephron 1997;75(3):372