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Endocrinology 151 , 143152 (2010)
Bull Exp Biol Med 2002;133:2746
p = 0.19) with no heterogeneity detected among studies (I 2 = 0%, p = 0.72) (Fig
Furthermore, in ECL1 of GCGR there are two glycine residues (G207 ECL1 , G219 ECL1 ) that disconnect the helical structure in the active state, whereas the G219 ECL1 is not conserved in GLP-1R and the helical conformation is relatively intact in this region of GLP-1R