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Abstract Background: Glucagon-like peptide-1 (GLP-1) receptor agonists, including tirzepatide, are increasingly prescribed for obesity and type 2 diabetes mellitus

Curr Biol (2014) 24:R45362.10.1016/j.cub.2014.03.034 10 GhezziP

812 Diabetic kidney disease occurs in patients with T2DM as a consequence of reduced kidney function, triggered by hypertensive nephrosclerosis and unresolved acute renal failure as the main culminating reasons

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Medical Contraindications These include a personal or family history of medullary thyroid carcinoma, a diagnosis of Multiple Endocrine Neoplasia syndrome type 2, or known hypersensitivity to semaglutide or other medication components

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