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Similar content being viewed by others Introduction Biological thiols, including glutathione (GSH), cysteine (Cys) and homocysteine (Hcy), play a pivotal role in many biological processes such as regulating redox homeostasis, detoxification and metabolism and as an active site of enzymes and cofactors 1,2
Only clinical trials investigating the effects of topical glutathione were included, excluding review articles, animal studies, and research on oral or intravenous glutathione
In addition, P53 could downregulate the SLC7A11 expression to inhibit cystine uptake, thereby affecting GPX4 activity and ultimately promoting the occurrence of ferroptosis (Jiang et al., 2015)
This brain tumor is highly proliferative and invasive and presents mechanisms of multidrug resistance (MDR)
Minimum assessment period for most peptides is 4 to 8 weeks
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