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Zudem moduliert es Wachstumsfaktoren wie VEGF (Vascular Endothelial Growth Factor)

Results from a partial coronary artery blockage

10.1021/acs.jmedchem.6b00975 114 OliveiraG.DiogoL.GrazinaM.GarciaP.AtadeA.MarquesC.et al (2005)

This figure represents 26.5% of all adults with diagnosed diabetes, a dramatic rise over a short study period

The specificity of the response was determined by treatment with an IGF-1R specific inhibitor, Picropodophyllin (PPP) that showed reduced BCL2 levels in GNE knockdown cells indicative of apoptotic response (Fig