flow trial semaglutide renal outcomes 2024 kidney nejm hazard ratio Effects of Once-Weekly on Disease by KDIGO Risk Category in the SUSTAIN 6 🚨 Journal Club: FLOW Trial – glp-1 receptor agonist kidney outcomes

This broad receptor distribution has prompted investigation into potential pleiotropic effects beyond glycemic control, including cardiovascular protection, renal benefits, and anti-inflammatory properties

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A critical consideration in interpreting metabolism studies is that substantial weight loss from any method typically results in decreased absolute energy expenditure

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Remember that every body responds differently, and what works for one person may require adjustment for another

GLP-1 medications, including semaglutide, are a class of drugs that act on receptors throughout the body, influencing insulin sensitivity, appetite regulation, inflammation and metabolic health