At the highest doses, retatrutide GI side effect rates are modestly higher than the other two medications
Weeks 3-4: Bloating often peaks during this period if you remain at the starting dose, or it resurges if you have just escalated
The analysis revealed four common adverse events across both genders: nausea, weight loss, vomiting, and diarrhea
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Your provider may reduce your dose, suggest a longer timeline before increasing your dose, or recommend other ways to manage these side effects
Mounjaro is a dual agonist , meaning it activates two receptors: GLP1 receptor GIP receptor The UK SmPC also lays out how dosing usually works (start low and increase slowly): starting dose 2.5 mg once weekly, then move to 5 mg, then step up in 2.5 mg increments if needed (with at least 4 weeks at each step)