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These compounds are also potent activators of the Nrf2 pathway and can inhibit inducible nitric oxide synthase (iNOS) (Liby and Sporn, 2012)
However, they suggest that ALCAR may be an important antidepressant therapy, either alone or in conjunction with other mood enhancers, especially in those with other medical conditions who may not tolerate high dose antidepressants
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As such, individuals adhering to plant-based diets should be mindful of their B12 intake
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Choi J, Liu R-M, Forman HJ
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