The rationale for injectable administration stems from the limitations of topical delivery
GGT is a glycosylated heterodimer protein formed by the non-covalent combination of a heavy chain subunit (relative molecular mass, 50,000-62,000) and a light chain subunit (relative molecular mass 22,000-30,000
Reconstitution, Storage, And Handling Both Retatrutide and Cagrilintide ship as a freeze-dried powder that has to be mixed with bacteriostatic water before any use
doi: 10.1016/j.neuint.2012.06.020 272 WillnerPScheel-KrgerJBelzungC
Its sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) was isolated from body protection compound (BPC) produced in the stomach
They may try to increase the likelihood of approval on the second try by including additional documentation or further evidence of medical necessity