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The starting structure of AdoCbl from the crystal structure was used as the starting geometry and the starting structure of OHCbl was created by replacing the adenosyl group with OH group in AdoCbl

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From day 1 of the experiment to day 5 the escape latency was found to remarkably decrease, however, escape latency in the APP/PS1 mice was higher than that of the wild type mice

Adequate levels of these neurotransmitters are important for maintaining good mood and overall mental well-being

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