How does semaglutide differ from other weight loss medications
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This may be the result of disturbed function of the ThDP-dependent 2-oxoglutarate dehydrogenase (Figure 1), as a universal effect of its inhibition is perturbation in relative amino acid abundance and a subsequent decrease in protein synthesis (196, 197)
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Results of this study suggest a modest increase in the risk of NAION among individuals with type 2 diabetes associated with semaglutide use, smaller than that previously reported, and warranting further investigation into the clinical implications of this association, the study concluded