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10.1016/S2213-8587(19)30192-5 Lancet Diabetes Endocrinol
As retatrutide is still in clinical development, site recommendations may be refined as further data become available
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Creatine supplementation helps maintain intramuscular energy stores (phosphocreatine), which supports continued muscle protein synthesis even when overall energy intake is reduced
Another study published in 2025 looked at a clinical trial from the FDA
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