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In STEP 1, participants without diabetes who received semaglutide 2.4 mg weekly lost an average of 14.9% of their body weight over 68 weeks compared to 2.4% with placebo
A frequently repeated "half-life ~12.8 days" figure circulates in vendor copy as a rationale for spaced or cyclical dosing
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Your provider reviews your history, medications, goals, and vitals to determine if treatment is appropriate
Typical descriptions: "Day 3 was when I really noticed," "By Thursday (injected Monday) I felt like a different person." Days 4-7: Plateau phase
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