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c HAMD-17, Hamilton Depression Scale (17-item)

Quick Answer: GLP-1 receptor agonists delay gastric emptying as a therapeutic mechanism that contributes to weight loss and glycemic control but can cause gastrointestinal symptoms and perioperative complications

Mulcahy, R.T., et al., Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

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The gradual dose escalation helps minimize gastrointestinal side effects, which are the most commonly reported adverse reactions