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High blood sugar and chronically elevated insulin can deplete vitamin B1, reducing the brains ability to produce energy
The type I IFN pathway is a key point for the start of the vitiligo immune response
Tirzepatide: Another Relevant Comparison Tirzepatide (Mounjaro/Zepbound), a dual GIP/GLP-1 agonist approved by the FDA, provides another useful reference point
Pioglitazone, a diabetes medication, may benefit selected patients with biopsy-proven NASH, but is also specialist-led and off-label , with potential risks including weight gain, fluid retention, heart failure, and increased fracture risk
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