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These modifications can change the conformation of proteins, resulting in dysfunction and the accumulation of misfolded proteins in the cytoplasm, which are implicated in cellular aging, apoptosis, and necrosis 89
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Most of the methods utilized titrimetric [3,5] colorimetric [2] spectrophotometric [6,7,8], high performance liquid chromatography [9], or radioisotopic techniques [10]
Deficiency can contribute to irritability, low mood, and increased stress
Most protocols last 4-8 weeks followed by rest periods
2011), antioxidant (Hoult and Pay 1996
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