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NICE guidelines (NG28) recommend GLP-1 agonists as second- or third-line therapy for type 2 diabetes when metformin and other agents are insufficient or unsuitable

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Its part of a class of banned substances called Non-Approved Substances, a catch-all for potentially performance-enhancing drugs that arent approved by any government regulatory authority

The main recognized subtypes include: Neuropathic POTS : Characterized by partial sympathetic denervation, particularly in the lower limbs, leading to blood pooling in the legs when standing

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