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M., Benayoun, B

They can promote mitochondrial biogenesis (increasing the number and function of mitochondria within cells), increase antioxidant activity, stabilize mitochondrial membranes, assist with ATP production, and modulate cell signaling and protection

Under mechanical stimulation from exercise, increased irisin levels facilitate the removal of excess iron ions from bone cells, thereby preventing ferroptosis and preserving bone structural integrity

Its greatest value may be as an adjunct to established cholesterol, glucose, inflammation, and kidney markers

Individual variation in response is significant and poorly characterized

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