One of the biggest deciding factors for patients can be the dosing frequency which is noted in the comparison table above
However, for those without a deficiency, such high doses are unnecessary and should be avoided without a doctor's recommendation
AOD-9604 is the most targeted option for fat metabolism, specifically designed to stimulate lipolysis and inhibit fat cell formation without elevating IGF-1 or disrupting insulin sensitivity, making it a relevant choice given that perimenopausal women already face increased insulin resistance risk
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And sometimes uncomfortable
While it does not directly cause nutrient loss, it often leads people to reduce fiber intake further, which compounds the problem of inadequate nutrition