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In other words, feeling sick is not what produces the result
In addition, one must gain FDA approval by clinically demonstrating that the delivery of the microbe-encapsulated GLP-1 through this oral route leaves the drug molecule itself unchanged (with no post-translational modifications), that it has a similar pharmacokinetic profile to the reference molecule, and that it shows no adverse effects
Participants taking the highest dose of Eli Lillys new GLP-1 drug lost an average of 28.7% of their body weight in a late-stage trial, putting it on track to be a heavyweight in the crowded world of weight-loss and diabetes treatments
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The variation comes from dispensing fees, markup percentage and chain-level negotiating power - the medication itself is the same Novo Nordisk product across every pharmacy in Canada
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