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In this global registration trial, where 84.0% of participants had a baseline BMI of 35 kg/m, each dose of retatrutide (9 mg and 12 mg) met all primary and key secondary endpoints, delivering significant weight loss and improvements in pain and physical function at 68 weeks using both the efficacy and treatment-regimen estimands

Most users find the GI effects tolerable and temporary

Have a history of pancreatitis (inflammation of the pancreas)

Ozempic, with the active ingredient semaglutide, belongs to a class of drugs known as GLP-1 receptor agonists

Exosome derived from murine adipose-derived stromal cells: Neuroprotective effect on in vitro model of amyotrophic lateral sclerosis