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And yet the stubborn fat remains

doi: 10.3390/ijms15034837

Plus, stimuli from the nose dont go through a peripheral nerve intermediary as do all other stimuli they shoot straight into the brain

In fact, reduced SPARC expression in mouse muscle upregulates atrogens, increases TGF-beta signaling, and decreases myofiber size, suggesting that SPARC deficiency leads to muscle atrophy (218)

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