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On one hand, FDA-approved obesity medications already exist (Wegovy, Zepbound, Foundayo), which historically has made priority review less likely for later entrants

However, their impact on endometrial receptivity and implantation remains unclear

A licensed provider will determine whether compounded semaglutide may be appropriate based on health history, goals, and individual needs

But there are many potential harms, especially when it comes to EDs. Keshen and coauthors provide detailed talking points for clinicians seeking to discuss GLP-1 RAs with patients who meet approved requirements for GLP-1 RA prescription or who are inappropriately using the medication to decrease binge eating. Prescribe Judiciously Wassenaar urged physicians to prescribe judiciously, after taking a history of disordered eating, and to adhere to evidence-based guidelines and not give GLP-1 RAs merely for cosmetic purposes

Your medical records can be transferred to continue GLP-1 therapy with another provider