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Medication, nutrition, and exercise should work together

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In addition to their weight loss benefits, these drugs also act through gut-brain signaling and central nervous system pathways involved in appetite, reward, and feeding behavior, although the extent to which individual agents cross the blood-brain barrier remains an active area of investigation

For example, ongoing research aims to identify new analogs or formulations of GLP-1 that may offer improved dosing regimens, reduced side effects, or enhanced efficacy

Bomba M, Granzotto A, Castelli V, Massetti N, Silvestri E, Canzoniero LMT, et al

GLP-1 receptor agonists are promising but unproven treatments for alcohol and substance use disorders