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Stopping abruptly may cause rebound appetite and weight regain

If you are curious about the science behind the molecule, our overview of what retatrutide is and how it works walks through the three-receptor mechanism in plain language

Semaglutide works by mimicking a natural hormone in the body called GLP-1, which helps regulate appetite and blood sugar levels, leading to reduced hunger and increased feelings of fullness

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doi: 10.1016/s0074-7742(02)50072-6, 61